Laboratory of Stem Cell Biology

Laboratory founded in  2007

Maria A. Lagarkova, Dr. Biol. Sci. (Head)

Selected Publications:

Korobko EV, Kiselev SL, Korobko IV. Dimerization properties of Rabaptin-5 and its isoforms. Biochemistry (Mosc). 2006 Dec;71(12):1307-11.

Korobko EV, Palgova IV, Kiselev SL, Korobko IV. Apoptotic cleavage of rabaptin-5-like proteins and a model for rabaptin-5 inactivation in apoptosis. Cell Cycle. 2006 Aug;5(16):1854-8. Epub 2006 Aug 15.

Lagarkova MA, Volchkov PY, Lyakisheva AV, Philonenko ES, Kiselev SL. Diverse epigenetic profile of novel human embryonic stem cell lines. Cell Cycle. 2006 Feb;5(4):416-20. Epub 2006 Feb 15.

Liepinsh DJ, Grivennikov SI, Klarmann KD, Lagarkova MA, Drutskaya MS, Lockett SJ, Tessarollo L, McAuliffe M, Keller JR, Kuprash DV, Nedospasov SA. Novel lymphotoxin alpha (LTalpha) knockout mice with unperturbed tumor necrosis factor expression: reassessing LTalpha biological functions. Mol Cell Biol. 2006 Jun;26(11):4214-25.

Ponomarenko NA, Durova OM, Vorobiev II, Belogurov AA Jr, Kurkova IN, Petrenko AG, Telegin GB, Suchkov SV, Kiselev SL, Lagarkova MA, Govorun VM, Serebryakova MV, Avalle B, Tornatore P, Karavanov A, Morse HC 3rd, Thomas D, Friboulet A, Gabibov AG. Autoantibodies to myelin basic protein catalyze site-specific degradation of their antigen. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):281-6.

Korobko IV, Korobko EV, Ninkina NN, Buchman VL, Kiselev SL. Phosphorylation of MAK-V protein kinase in mammalian cells.  Dokl Biochem Biophys. 2007 Jan-Feb;412:37-9.

Shebzukhov YV, Koroleva EP, Khlgatian SV, Belousov PV, Sazykin AY, Kadachigova TS, Pomerantseva EA,Lagarkova MA, Nedospasov SA, Kuprash DV. RAP80/UIMC1 as cancer-associated antigen: alternative splice variants and their immunogenicity. Cancer Lett. 2007 Oct 8;255(2):255-62.

Korneev SA, Korneeva EI, Lagarkova MA, Kiselev SL, Critchley G, O'Shea M. Novel noncoding antisense RNA transcribed from human anti-NOS2A locus is differentially regulated during neuronal differentiation of embryonic stem cells. RNA. 2008 Oct;14(10):2030-7.

Lagarkova MA, Volchkov PY, Philonenko ES, Kiselev SL. Efficient differentiation of hESCs into endothelial cells in vitro is secured by epigenetic changes. Cell Cycle. 2008 Sep 15;7(18):2929-35.

Lagarkova MA, Volchkov PY, Philonenko ES, Pfannkuche K, Prokhorovich MA, Zabotina T, Hescheler J,Kiselev SL. CD 30 is a marker of undifferentiated human embryonic stem cells rather than a biomarker of transformed hESCs. Cell Cycle.2008 Nov 15;7(22):3610-2.

Mikhaylova IN, Kovalevsky DA, Morozova LF, Golubeva VA, Cheremushkin EA, Lukashina MI, Voronina ES, Burova OS, Utyashev IA, Kiselev SL, Demidov LV, Beabealashvilli RSh, Baryshnikov AY. Cancer/testis genes expression in human melanoma cell lines. Melanoma Res. 2008 Oct;18(5):303-13.

Petrunia IV, Frolova OY, Komarova TV, Kiselev SL, Citovsky V, Dorokhov YL.Agrobacterium tumefaciens-induced bacteraemia does not lead to reporter gene expression in mouse organs. PLoS One. 2008 Jun 4;3(6):2352.

Lagarkova MA, Shutova MV, Bogomazova AN, Vassina EM, Glazov EA, Zhang P, Rizvanov AA,Chestkov IV, Kiselev SL. Induction of pluripotency in human endothelial cells resets epigenetic profile on genome scale. Cell Cycle. 2010 Mar;9(5):937-46.

Lagarkova М.A., Eremeev A.V., Svetlakov A.V., Rubtsov N.B., Kiselev S.L. Human embryonic stem cell lines isolation, cultivation, and characterization. // In Vitro Cellular and Developmental Biology-Animal. 2010. Springer. Special issue, 46(3-4): рp. 132-138.

Aseeva EA, Snigiryova GP, Neverova AL, Bogomazova AN, Novitskaya NN, Khazins ED, Domracheva EV. New type of cells with multiple chromosome rearrangements. Appl Radiat Isot. 2010 Apr-May;68(4-5):844-7. PubMed PMID: 20031432.